Arthrohills Capsule: Clinical Study Report Summary for Doctors
Joint care
Arthrohills Capsule: Clinical Study Report Summary for Doctors
Arthrohills Capsule is a Herbal Hills Ayurvedic joint-care medicine prepared by the Siddha Ghruta method in a cow ghee base. It is backed by two clinical studies: a CTRI-registered 90-day trial in 33 adults with mild to moderate knee osteoarthritis, where the mean VAS pain score fell from 68.93 to 31.88, and a 21-day safety study in 30 adults that recorded no adverse drug reactions.
The study in brief
| Field | Study A (registered trial) | Study B (published safety study) |
|---|---|---|
| Study title | An Open Label, Prospective, Multicentre, Clinical study to evaluate efficacy and safety of Arthrohills Capsules in subjects suffering from Osteoarthritis of Knee(s) | A Safety Evaluation and Tolerability of Arthohills Capsule an Ayurveda Formulation in Osteoarthritis Subjects |
| Registration / journal | CTRI/2017/06/008786, registered 08/06/2017 | Int J Res Ayurveda Med Sci 2021; 4(1): 22–27 (ISSN 2582-2748) |
| Design | Open-label, prospective, single-arm; IEC approved | Observational, non-comparative, prospective; IEC approved, ICMR guidelines |
| Participants | 33 adults with mild to moderate knee osteoarthritis | 30 adults aged 40–70 with knee osteoarthritis |
| Dose and duration | 2 capsules daily, morning, empty stomach, with lukewarm water or milk; 90 days | 2 capsules (500 mg) twice a day; 21 days |
| Measures | VAS pain, WOMAC, time to walk 50 feet, quality of life, global evaluation, adverse events, lab tests | VAS pain, WOMAC (pain, stiffness, physical function), haematology, knee X-ray, adverse events |
| Sponsor | Herbal Hills (Isha Agro Developers Pvt Ltd) | Herbal Hills; conducted at Vishwanand Kendra, Pune |
Composition
Each soft gel capsule contains Arthrohills Ghruta 500 mg, processed by the Siddha Ghruta method with cow ghee and cow milk and the following herbs (as published):
| Ingredient | Botanical name | Part | Quantity |
|---|---|---|---|
| Sunthee | Zingiber officinale | Rhizome | 22.75 mg |
| Shallaki | Boswellia serrata | Gum resin | 45.45 mg |
| Shuddha Guggul | Balsamodendron mukul | Gum resin | 45.45 mg |
| Shuddha Laksha | Laccifer lacca | Resin | 45.45 mg |
| Nirgundee | Vitex negundo | Whole plant | 45.45 mg |
| Methi | Trigonella foenum-graecum | Seeds | 45.45 mg |
| Asthishrunkhala | Vitis quadrangularis | Stem | 45.45 mg |
| Maharasnadi | Generic preparation | — | 90.90 mg |
| Dashmooladi | Generic preparation | — | 90.90 mg |
| Chopchinee | Rheum emodi | Root | 22.75 mg |
| Go Ghrit / Go Dugdha | Cow ghee / cow milk | — | Processing base |
Outcome measures
Both studies used the Visual Analogue Scale (VAS), where participants rate knee pain during weight-bearing activity, and the WOMAC index, a widely used questionnaire that scores knee pain, stiffness and physical function. Study A also timed a 50-foot walk and recorded quality of life and the investigator's global assessment. Study B repeated blood tests and knee X-rays at day 21 to check safety.
Safety and tolerability
In Study B, all 30 participants completed the study, blood tests and knee X-rays at day 21 stayed within normal limits and comparable with baseline, and no adverse drug reactions were recorded. The Study A summary reports that the formulation was well tolerated and that most adverse events recorded were not related to the study product. To fill: exact adverse-event wording from the full CTRI study report
Limits of the evidence
Neither study had a placebo or comparator group, both were sponsor-funded, and sample sizes were small (30–33). Study B lasted only 21 days. The results describe what happened in these study groups and are not a guarantee of results for every user.
Results reported
| Measure | Baseline | End of study | Change |
|---|---|---|---|
| Study A: VAS pain score (mean ± SD) | 68.93 ± 15.40 | 31.88 ± 14.47 (day 90) | −53.7%, p<0.05 |
| Study A: WOMAC pain score | — | — | −48.84% |
| Study A: WOMAC stiffness score | — | — | −53.95% |
| Study A: investigator global assessment | — | — | 81.81% showed minimum to much improvement |
| Study A: needed paracetamol for pain | — | — | 6.06% of participants |
| Study B: VAS pain score | 40.28 ± 4.78 | 23.78 ± 2.01 (day 21) | −41.0%, p<0.001 |
| Study B: WOMAC total | 48.21 | 27.12 | −43.7%, p<0.001 |
| Study B: WOMAC pain sub-score | 10.22 | 4.11 | −59.8% |
| Study B: WOMAC stiffness sub-score | 3.05 | 1.03 | −66.2% |
| Study B: WOMAC physical function | 34.11 | 21.67 | −36.5% |
In Study A, mean knee pain on the VAS fell steadily at every 15-day visit, from 68.93 at baseline to 31.88 at day 90. In Study B, VAS pain fell from 40.28 to 23.78 over 21 days, and every WOMAC sub-score improved significantly (p<0.001). Percentages in the table are calculated from the published means.
Study the report. Then try it.
Ask for the full study report and a free trial sample of Arthrohills Capsule to evaluate in your practice — through your Herbal Hills wholesale contact, on +91 22 2868 6868 or at hhwholesale@herbalhills.in.
Stocking Arthrohills Capsule in your practice
Arthrohills Capsule is available to doctors, clinics and stockists through Herbal Hills Prime. Ask your wholesale contact for trade terms on these packs.
Arthrohills 30 Soft Capsules — pack of 5View listing →
Arthrohills 60 Soft Capsules — pack of 5View listing →
Arthrohills 900 Soft Capsules — value packView listing →
Arthrohills 900 Soft Capsules — pack of 2View listing →
Please note: Herbal Hills formulations, pack formats and new product launches are developed, manufactured and supplied subject to the applicable licences, applications and regulatory approvals. The clinical study documentation on this page is shown as supporting evidence for the formulation that was studied. It does not mean that every pack, variant or newly branded product has been independently clinically tested.
Frequently asked questions
What did the Arthrohills Capsule trial measure?
Knee pain on the Visual Analogue Scale, the WOMAC index for pain, stiffness and physical function, a timed 50-foot walk, quality of life, the investigator's global assessment, adverse events and laboratory tests over 90 days.
Can I get a free trial sample of Arthrohills Capsule?
Yes. Doctors can ask their Herbal Hills wholesale contact, call +91 22 2868 6868 or email hhwholesale@herbalhills.in for a free trial sample and the full CTRI study report.
Read more on our blog: To fill: blog title + URL
Study reference: Study A: CTRI/2017/06/008786 (registered 08/06/2017), Clinical Trials Registry – India. Study B: Mandlecha A, Mujawar G. A Safety Evaluation and Tolerability of Arthohills Capsule an Ayurveda Formulation in Osteoarthritis Subjects. Int J Res Ayurveda Med Sci 2021; 4(1): 22–27.
Important information for healthcare professionals: This page summarises published clinical research on Herbal Hills Ayurvedic medicines for doctors, clinics and trade buyers. It is not an advertisement to the public and does not claim that any product diagnoses, treats, cures or prevents any disease. Study results describe the participants studied and individual results vary.
